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This exploration seeks to pave the way for innovative therapeutic strategies that not only mitigate the adverse effects of radiation on healthy brain tissue, but also enhance the efficacy of radiation therapy against tumors, marking a significant stride towards improving patient outcomes in head and neck cancer treatment

Carreno-Muoz et al

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Given that such data are not entirely homogenous with RCTs in terms of design and control conditions, they are best utilized as exploratory indicators of potential effect ceilings and accessibility to calibrate clinical expectations, rather than as direct points of comparison for placebo-controlled RCTs